What disease does christina applegate have

As of 22 September 2026, Christina Applegate continues to be a prominent advocate for Multiple Sclerosis (MS) awareness, a condition she publicly disclosed in August 2021. The actress, known for her roles in "Dead to Me" and "Married... with Children," has been candid about the physical and emotional toll of the autoimmune disease, which affects the central nervous system. Throughout 2026, Applegate has remained vocal about the daily challenges of living with MS, including mobility issues and the necessity of using assistive devices. Her journey has been characterized by a blend of humor and raw honesty, as she frequently discusses the unpredictable nature of flare-ups and the adjustments required in her professional and personal life. Despite stepping back from traditional on-camera acting roles due to the fatigue and physical limitations associated with the disease, she remains active in the entertainment industry through voice work and advocacy. Her public transparency has provided significant visibility for the MS community, helping to destigmatize the condition while highlighting the urgent need for continued research and accessible healthcare support for those diagnosed with chronic neurological disorders.